Best Song
- Eminem (featuring Rihanna) — "Love the Way You Lie"
- Lady Gaga — "Bad Romance"
- Katy Perry (featuring Snoop Dogg) — "California Gurls"
- Rihanna — "Rude Boy"
- Usher (featuring will.i.am) — "OMG"
Best Video
- 30 Seconds to Mars — "Kings and Queens"
- Eminem (featuring Rihanna) — "Love the Way You Lie"
- Lady Gaga (featuring Beyoncé) — "Telephone"
- Katy Perry (featuring Snoop Dogg) — "California Gurls"
- Plan B — "Prayin'"
Best Female
Best Male
Best Pop
Best Rock
Best Alternative
Best Hip-Hop
Best New Act
Best Live Act
Best World Stage Performance
Best Push Act
- B.o.B
- Justin Bieber
- Alexandra Burke
- Jason Derülo
- The Drums
- Hurts
- Ke$ha
- Mike Posner
- Professor Green
- Selena Gomez & the Scene